Wapl is an essential regulator of chromatin structure and chromosome segregation.
作者： Antonio Tedeschi , Gordana Wutz , Sébastien Huet , Markus Jaritz , Annelie Wuensche
DOI: 10.1038/NATURE12471
关键词: Chromatid 、 DNA 、 Chromosome segregation 、 Chromatin 、 Separase 、 Biology 、 Prophase 、 Cohesin 、 Genetics 、 Base pair
摘要: Mammalian genomes contain several billion base pairs of DNA that are packaged in chromatin fibres. At selected gene loci, cohesin complexes have been proposed to arrange these fibres into higher-or ...
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