Defining the learning curve for multiparametric magnetic resonance imaging (MRI) of the prostate using MRI-transrectal ultrasonography (TRUS) fusion-guided transperineal prostate biopsies as a validation tool.

摘要: Objectives To determine the accuracy of multiparametric magnetic resonance imaging (mpMRI) during learning curve radiologists using MRI targeted, transrectal ultrasonography (TRUS) guided transperineal fusion biopsy (MTTP) for validation. Patients and Methods Prospective data on 340 men who underwent mpMRI (T2-weighted diffusion-weighted MRI) followed by MTTP prostate biopsy, was collected according to Ginsburg Study Group Standards Reporting Diagnostic Accuracy standards. were reported two experienced scored a Likert scale. Biopsies performed consultant urologists not ‘blinded’ result had both targeted systematic sector biopsies, which reviewed dedicated uropathologist. The cohorts divided into groups representing five consecutive time intervals in study. Sensitivity specificity positive reports, cancer detection MRI, distribution significant Gleason score negative with false calculated. Data sequentially analysed determined comparing first last group. Results We detected 64 patients from A (91%) 52 E (74%). rate increased 42% (27/64) 81% (42/52) (P 3+3) 88.9% compared 66.6% A. Conclusion We demonstrate an improvement reporting over time, suggesting technique. With improved predictive value cancer, decision should be based patient/surgeon factors risk attributes alongside findings.