The Notch signaling pathway controls short-lived effector CD8+ T cell differentiation but is dispensable for memory generation.
作者： Mélissa Mathieu , Frédéric Duval , Jean-François Daudelin , Nathalie Labrecque
关键词:
摘要: … , Notch deficiency did not alter the rate of memory CD8 + T cell generation. Moreover, we reveal that the Notch signaling … critical functions for the Notch signaling pathway during effector …
aai.org
jimmunol.org 参考文章(62)
Emanuela Anastasi, Antonio F. Campese, Diana Bellavia, Angela Bulotta, Anna Balestri, Monica Pascucci, Saula Checquolo, Roberto Gradini, Urban Lendahl, Luigi Frati, Alberto Gulino, Umberto Di Mario, Isabella Screpanti, Expression of Activated Notch3 in Transgenic Mice Enhances Generation of T Regulatory Cells and Protects against Experimental Autoimmune Diabetes The Journal of Immunology. ,vol. 171, pp. 4504- 4511 ,(2003) , 10.4049/JIMMUNOL.171.9.4504
John T. Harty, Douglas W. White, Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha Journal of Immunology. ,vol. 160, pp. 898- 905 ,(1998)
Scott H. Adler, Elise Chiffoleau, Lanwei Xu, Nicole M. Dalton, Jennifer M. Burg, Andrew D. Wells, Michael S. Wolfe, Laurence A. Turka, Warren S. Pear, Notch Signaling Augments T Cell Responsiveness by Enhancing CD25 Expression Journal of Immunology. ,vol. 171, pp. 2896- 2903 ,(2003) , 10.4049/JIMMUNOL.171.6.2896
Emma Fiorini, Estelle Merck, Anne Wilson, Isabel Ferrero, Wei Jiang, Ute Koch, Floriane Auderset, Elisa Laurenti, Fabienne Tacchini-Cottier, Michel Pierres, Freddy Radtke, Sanjiv A. Luther, H. Robson MacDonald, Dynamic Regulation of Notch 1 and Notch 2 Surface Expression during T Cell Development and Activation Revealed by Novel Monoclonal Antibodies Journal of Immunology. ,vol. 183, pp. 7212- 7222 ,(2009) , 10.4049/JIMMUNOL.0902432
Ok Hyun Cho, Hyun Mu Shin, Lucio Miele, Todd E. Golde, Abdul Fauq, Lisa M. Minter, Barbara A. Osborne, Notch Regulates Cytolytic Effector Function in CD8+ T Cells Journal of Immunology. ,vol. 182, pp. 3380- 3389 ,(2009) , 10.4049/JIMMUNOL.0802598
Eui Ho Kim, Jeremy A. Sullivan, Erin H. Plisch, Melba Marie Tejera, Anna Jatzek, Kwan Yong Choi, M. Suresh, Signal Integration by Akt Regulates CD8 T Cell Effector and Memory Differentiation Journal of Immunology. ,vol. 188, pp. 4305- 4314 ,(2012) , 10.4049/JIMMUNOL.1103568
Salix Boulet, Jean-François Daudelin, Nathalie Labrecque, IL-2 Induction of Blimp-1 Is a Key In Vivo Signal for CD8 + Short-Lived Effector T Cell Differentiation Journal of Immunology. ,vol. 193, pp. 1847- 1854 ,(2014) , 10.4049/JIMMUNOL.1302365
Marie-Hélène Lacombe, Marie-Pierre Hardy, Julie Rooney, Nathalie Labrecque, IL-7 Receptor Expression Levels Do Not Identify CD8+ Memory T Lymphocyte Precursors following Peptide Immunization Journal of Immunology. ,vol. 175, pp. 4400- 4407 ,(2005) , 10.4049/JIMMUNOL.175.7.4400
Kelly A. N. Messingham, Vladimir P. Badovinac, Ali Jabbari, John T. Harty, A Role for IFN-γ from Antigen-Specific CD8+ T Cells in Protective Immunity to Listeria monocytogenes Journal of Immunology. ,vol. 179, pp. 2457- 2466 ,(2007) , 10.4049/JIMMUNOL.179.4.2457
Kristin A. Hogquist, Stephen C. Jameson, William R. Heath, Jane L. Howard, Michael J. Bevan, Francis R. Carbone, T cell receptor antagonist peptides induce positive selection Cell. ,vol. 76, pp. 17- 27 ,(1994) , 10.1016/0092-8674(94)90169-4