The biomechanical effect of high-pressure irrigation on diaphyseal fracture healing in vivo.

摘要: OBJECTIVES To evaluate the effect of both high-pressure pulsatile lavage and bulb syringe irrigation on biomechanical parameters fracture healing using an in vivo open noncontaminated diaphyseal femoral model rats. BACKGROUND The utility soft tissue debridement has been extrapolated to a similar perceived benefit bone. However, there have several reports possible deleterious that may bone architecture, intramedullary bacterial contaminant seeding, healing. Although previous histologic study suggests damage architecture impairment early formation, it remains unclear whether these microscopic findings translate detectable decline strength fracture. our knowledge, no effects fractures. MATERIALS AND METHODS Using sterile technique, standard transverse mid-shaft femur fractures were created thirty-six rats randomized into three groups: control group underwent retrograde pinning only; identical procedures as group, except osteotomy site was irrigated with lavage, respectively, before insertion pin. Six from each killed at weeks six weeks, femora mechanically tested bending. RESULTS Mechanical testing revealed peak bending force (17.7 +/- 10.2 N) stiffness (21.2 5.1 N/mm) significantly lower when compared (peak force, 28.1 5.9 N; stiffness, 31.4 5.8 27.7 3.3 23.6 4.5 groups (p < 0.05). 37 percent 32 after not present weeks. did reveal trend toward groups, but differences statistically significant 95 level. CONCLUSIONS use negative impact mechanical callous during phases (three weeks) appears is apparent late (six Further required presence wound contamination, comminution, damage. CLINICAL SIGNIFICANCE this suggest selective management warranted. In situations which be healing, alternative strategies optimize removal tissues while preserving will need investigated.