Lack of Interaction between Pantoprazole and Ethanol A Randomised, Double-Blind, Placebo-Controlled Study in Healthy Volunteers

作者: H. Heinze , R. Fischer , R. Pf??tzer , S. Teyssen , M.V. Singer

DOI: 10.2165/00044011-200121050-00004

关键词:

摘要: Objective: To assess the effect of proton pump inhibitor pantoprazole on pharmacokinetics ethanol.

参考文章(34)
Gabriele Pozzato, L. Battiston, M. Moretti, P. Tulissi, Lansoprazole and ethanol metabolism: comparison with omeprazole and cimetidine. Pharmacology & Toxicology. ,vol. 81, pp. 247- 252 ,(1997)
Klaus-Wolfgang Herberg, Manfred Hartmann, Barbara Neukirchen, Reinhold L??hmann, Kathy B. Thomas, Wilhelm Wurst, Pantoprazole Does Not Affect Performance in Traffic- Related Safety Tests Clinical Drug Investigation. ,vol. 16, pp. 63- 70 ,(1998) , 10.2165/00044011-199816010-00008
H Bliesath, R Huber, V W Steinijans, M Hartmann, H W Radtke, W Wurst, K Zech, Lack of pantoprazole drug interactions in man: an updated review International Journal of Clinical Pharmacology and Therapeutics. ,vol. 34, pp. 243- 262 ,(1996)
Joan Caballeria, Enrique Baraona, Miquel Rodamilans, Charles S. Lieber, Effects of Cimetidine on Gastric Alcohol Dehydrogenase Activity and Blood Ethanol Levels Gastroenterology. ,vol. 96, pp. 388- 392 ,(1989) , 10.1016/0016-5085(89)91562-X
Fox Mj, Nambi P, Wetherington Jd, Palmer Rh, Frank Wo, Effects of various concomitant medications on gastric alcohol dehydrogenase and the first-pass metabolism of ethanol. The American Journal of Gastroenterology. ,vol. 86, pp. 1749- 1755 ,(1991)
Volker W. Steinijans, Dieter Hauschke, Robert Schall, International Harmonization of Regulatory Requirements for Average Bioequivalence and Current Issues in Individual Bioequivalence Drug Information Journal. ,vol. 29, pp. 1055- 1062 ,(1995) , 10.1177/009286159502900326
Paul Richardson, Christopher J. Hawkey, William A. Stack, Proton pump inhibitors. Pharmacology and rationale for use in gastrointestinal disorders. Drugs. ,vol. 56, pp. 307- 335 ,(1998) , 10.2165/00003495-199856030-00002
PS Haber, RT Gentry, KM Mak, SA Mirmiran-Yazdy, RJ Greenstein, CS Lieber, Metabolism of alcohol by human gastric cells: Relation to first-pass metabolism Gastroenterology. ,vol. 111, pp. 863- 870 ,(1996) , 10.1016/S0016-5085(96)70054-9
Stephen Toon, Azhar Z Khan, Beverly I Holt, Francis G P Mullins, Stephen J Langley, Malcolm M Rowland, Absence of effect of ranitidine on blood alcohol concentrations when taken morning, midday, or evening with or without food Clinical Pharmacology and Therapeutics. ,vol. 55, pp. 385- 391 ,(1994) , 10.1038/CLPT.1994.46