Prognostic significance of high-resolution CT findings in small peripheral adenocarcinoma of the lung: a retrospective study on 64 patients

摘要: Objective: We studied the prognostic importance of high-resolution CT (HRCT) findings in lung adenocarcinomas. Patients and methods: HRCT (lesion size, percentage ground-glass opacity (GGO) areas lesion, presence or absence lobulation, coarse spiculation, air space, pleural tag, multiplicity lesion), clinical data (age surgical method), pathologic (tumor subtypes nodal metastasis) 64 consecutive patients with peripheral adenocarcinomas 20 mm less (mean, 13 mm), including 36 women 28 men a mean age years were analyzed correlated survival using Kaplan–Meier method stepwise Cox proportional hazards modeling. Follow-up periods ranged from 6 to 45 months 22 months). Tumors classified into six (types A–F) according tumor growth patterns defined by Noguchi et al. Results: Six (9%) died cancer. In univariate analyses, significant difference was noted for lesion size (P=0.043), GGO (P=0.005), (P=0.006). Lesion 57% (n=36), type A (n=16) B indicated significantly better survival. multivariate analyses these three parameters as independent variables, only factor (P=0.044, relative risk=0.95). Conclusion: measured on may have an significance small lung.