Prognostic factors for patients with advanced non-small cell lung cancer: univariate and multivariate analyses including recursive partitioning and amalgamation.
作者： Nagio Takigawa , Yoshihiko Segawa , Masayuki Okahara , Yoshinobu Maeda , Ichiro Takata
DOI: 10.1016/0169-5002(96)00571-5
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摘要: Abstract In an attempt to determine the prognostic significance of pretreatment factors for patients with advanced non-small cell lung cancer (NSCLC), 24 clinical variables were analyzed 185 NSCLC who underwent chemotherapy and/or radiotherapy between 1985 and 1994. Following univariate analysis, we applied two multivariate statistical techniques. a Cox regression model, independently significant influencing patient survival included performance status (PS), disease stage, hemoglobin level, serum calcium level. Recursive partitioning amalgamation (RPA) resulted in three distinct subgroups based on PS, weight loss, The best was observed good PS Stage III had level > 11 g/dl. worst poor presence loss irrespective stage. All other intermediate prognosis. Median times 95.1 weeks, 17.1 weeks 39.3 respectively ( P
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