Hypophosphatemia in critically ill children: prevalence and associated risk factors.

摘要: Background: Hypophosphatemia is a disorder with potential complications and often unrecognized in critically ill patients. Aims: To identify the prevalence of hypophosphatemia risk factors associated to this children. Methods: In prospective cohort study, 82 children admitted consecutively pediatric intensive care unit (ICU) were monitored regarding phosphorus serum levels during first 10 days admission. The following variables analyzed as independent for hypophosphatemia: age, gender, diagnosis at admission, malnutrition, intake, clinical severity score admission (pediatric index mortality 2) daily scores (Pediatric Logistic Organ Dysfunction), sepsis, use dopamine, furosemide steroids, starvation period, refeeding. Children z less than 2 expected weight age or body mass (National Center Health Statistics, 2000) considered malnourished. Variables significantly by bivariate analysis (p < 0.1) included multiple logistic regression model. Results: rate was 61% ICU stay, 12 patients developed study period. Malnutrition present 39.1% patients, sera concentration lower malnourished wellnourished (2.6 0.7 mg/dL vs. 3.5 0.8 mg/dL, p 0.01). model indicated acute respiratory disease (odds ratio: 3.22; confidence interval: 1.03‐10.1; 0.04), dopamine 8.65; 1.58‐47.3; 0.01), malnutrition 3.96; 1.19‐13.3; 0.02) hypophosphatemia. None other discriminated Conclusions: common hospitalization disease, malnutrition. These should be taken into account follow up children, especially when these conditions are found together. (Pediatr Crit Care Med 2009; 10:234‐238)