Fabrication and Characteristic Analysis for Enzymatic Glucose Biosensor Modified by Graphene Oxide and Magnetic Beads Based on Microfluidic Framework
作者： Jung-Chuan Chou , Jian-Syun Chen , Yi-Hung Liao , Chih-Hsien Lai , Siao-Jie Yan
DOI: 10.1109/JSEN.2017.2654492
关键词:
摘要: The indium gallium zinc oxide (IGZO) was adopted as enzymatic glucose sensing membrane and a screen-printed technology used to complete fabrication of sensor in this paper. There are some drawbacks for most the biosensors, such insufficient area weak immobilization strength, formed between oxidase (GOx) support materials. For improving biosensor, graphene (GO) directly dropped on IGZO improve magnetic beads (MBs) were combined with GOx by covalent bonding enhance strength GOx. In addition, biosensor modified GO MBs integrated microfluidic framework order investigate characteristics under dynamic conditions. According experimental results, optimal average sensitivity linearity 12.383 mV/mM 0.999 at 25- $\mu \text{L}$ /min flow rate, respectively.
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