Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers

作者: William Peter Van Antwerp , Stephen M. Lane , David J. Vachon , John Joseph Mastrototaro , Joseph C. Walsh

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摘要: Fluorescent biosensor molecules, fluorescent biosensors and systems, as well methods of making using these molecules systems are described. Embodiments exhibit fluorescence emission at wavelengths greater than about 650 nm. Typical include a fluorophore that includes an iminium ion, linker moiety group is anilinic type relationship to the boronate substrate recognition/binding moiety, which binds glucose. The modulated by presence or absence polyhydroxylated analytes such This property invention, their ability emit light nm, renders particularly well-suited for detecting measuring in-vivo glucose concentrations.

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