摘要: Several options are available today in the treatment of advanced colorectal cancer: traditional chemotherapeutic regimens, targeted therapies, and their combinations. Panitumumab is a new, fully human anti-EGFR monoclonal antibody, what well-tolerated, effective as single agent chemotherapy refractory patients different The clinical response restricted to tumors with wild-type RAS, therefore RAS status should be checked before treatment.