Tissue-Engineering von respiratorischem Epithel
作者： M. Bücheler , U. von Foerster , A. Haisch , F. Bootz , S. Lang
DOI: 10.1007/S00106-008-1677-2
关键词:
摘要: Reconstruction of long tracheal defects remains an unsolved surgical problem. Tissue engineering respiratory epithelium is therefore utmost and scientific interest. Successful cultivation reproduction in vitro crucial to seed scaffolds various biomaterials with functionally active mucosa. Most frequently, the suspension culture as well tissue or explant cultures are used. Collagenous matrices, synthetic biodegradable polymers, serve carriers studies. It essential for clinical practice that mechanically stable be developed resorbable term cartilaginous constructs produced employed which seeded before implantation. Vascularization a bioartificial matrix substitution also prerequisite integration into recipient organism. Here, state art research, perspectives limitations reviewed.
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