作者: Jaana Willberg , Stina Syrjänen , Marketta Hormia
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摘要: Background: The integrity of junctional epithelium (JE) and a firm epithelial adhesion to the tooth surface are maintained by balance between cell proliferation death. Maintaining JE structure is essential for protection periodontal connective tissues against oral microbes. In this study, proliferative activity expression caspase 3, cysteine protease associated with death, were studied in rat other structures during molar development. Methods: Fourteen rats aged 10 70 days injected bromodeoxyuridine (BrdU). Samples first second molars selected immunohistochemical staining. BrdU incorporation was (OE) covering erupting tooth, reduced enamel (REE), gingival (GE), sulcular (SE), JE. also subjected analysis proliferating nuclear antigen (PCNA) 3. Results: basal cells GE actively proliferating, but JE, only few positive or PCNA immunostaining. Some outer REE eruption. Caspase 3 specific areas after completion amelogenesis. Conclusions: Results showed slow However, studies on cellular turnover migration needed understand tissue homeostasis area.