7-((5-Nitrothiophen-2-yl)methoxy)-3H-phenoxazin-3-one as a spectroscopic off–on probe for highly sensitive and selective detection of nitroreductase

作者: Zhao Li , Xinghui Gao , Wen Shi , Xiaohua Li , Huimin Ma

DOI: 10.1039/C3CC42610F

关键词:

摘要: A new spectroscopic off–on probe, 7-((5-nitrothiophen-2-yl)methoxy)-3H-phenoxazin-3-one, is developed and applied to real-time detection of nitroreductase produced by Escherichia coli.

参考文章(29)
William D. Won, Robert J. Heckly, Donald J. Glover, John C. Hoffsommer, Metabolic Disposition of 2, 4, 6-Trinitrotoluene Applied Microbiology. ,vol. 27, pp. 513- 516 ,(1974) , 10.1128/AM.27.3.513-516.1974
María Dolores Roldán, Eva Pérez-Reinado, Francisco Castillo, Conrado Moreno-Vivián, Reduction of polynitroaromatic compounds: the bacterial nitroreductases. Fems Microbiology Reviews. ,vol. 32, pp. 474- 500 ,(2008) , 10.1111/J.1574-6976.2008.00107.X
J Whiteway, P Koziarz, J Veall, N Sandhu, P Kumar, B Hoecher, IB107609 Lambert, None, Oxygen-insensitive nitroreductases: analysis of the roles of nfsA and nfsB in development of resistance to 5-nitrofuran derivatives in Escherichia coli. Journal of Bacteriology. ,vol. 180, pp. 5529- 5539 ,(1998) , 10.1128/JB.180.21.5529-5539.1998
Marie Cellier, Olivier J. Fabrega, Elizabeth Fazackerley, Arthur L. James, Sylvain Orenga, John D. Perry, Vindhya L. Salwatura, Stephen P. Stanforth, 2-Arylbenzothiazole, benzoxazole and benzimidazole derivatives as fluorogenic substrates for the detection of nitroreductase and aminopeptidase activity in clinically important bacteria. Bioorganic & Medicinal Chemistry. ,vol. 19, pp. 2903- 2910 ,(2011) , 10.1016/J.BMC.2011.03.043
Ajay N. Jain, Surflex: fully automatic flexible molecular docking using a molecular similarity-based search engine. Journal of Medicinal Chemistry. ,vol. 46, pp. 499- 511 ,(2003) , 10.1021/JM020406H
Lei Cui, Ye Zhong, Weiping Zhu, Yufang Xu, Qingshan Du, Xin Wang, Xuhong Qian, Yi Xiao, A new prodrug-derived ratiometric fluorescent probe for hypoxia: high selectivity of nitroreductase and imaging in tumor cell. Organic Letters. ,vol. 13, pp. 928- 931 ,(2011) , 10.1021/OL102975T
Duan Feng, Yangyang Zhang, Tingting Feng, Wen Shi, Xiaohua Li, Huimin Ma, A graphene oxide–peptide fluorescence sensor tailor-made for simple and sensitive detection of matrix metalloproteinase 2 Chemical Communications. ,vol. 47, pp. 10680- 10682 ,(2011) , 10.1039/C1CC13975D
Hun-Chung Huang, Kun-Li Wang, Sheng-Tung Huang, Hsin-Yi Lin, Chun-Mao Lin, Development of a sensitive long-wavelength fluorogenic probe for nitroreductase: A new fluorimetric indictor for analyte determination by dehydrogenase-coupled biosensors Biosensors and Bioelectronics. ,vol. 26, pp. 3511- 3516 ,(2011) , 10.1016/J.BIOS.2011.01.036
Paul R. Race, Andrew L. Lovering, Richard M. Green, Abdelmijd Ossor, Scott A. White, Peter F. Searle, Christopher J. Wrighton, Eva I. Hyde, Structural and Mechanistic Studies of Escherichia coli Nitroreductase with the Antibiotic Nitrofurazone REVERSED BINDING ORIENTATIONS IN DIFFERENT REDOX STATES OF THE ENZYME Journal of Biological Chemistry. ,vol. 280, pp. 13256- 13264 ,(2005) , 10.1074/JBC.M409652200