Case-control study of risk factors for incident HIV infection in rural Uganda.

摘要: A case-control study was conducted to identify risk factors associated with HIV incidence in a rural Ugandan population. Men and women who seroconverted between 1990 1997 (cases) seronegative subjects (controls) were drawn from general population cohort of approximately 5000 adults southwestern Uganda. Information on ascertained through detailed interview physical examination by clinicians blind the status. All patients interviewed within 2 years their estimated date seroconversion. Data available 130 men (37 cases 93 controls) 133 (46 87 controls). There significantly higher infection (odds ratio [OR] 6.51; 95% confidence interval [CI] 1.06-39.84) (OR 4.75; CI 1.26-17.9) unmarried steady relationship divorced separated or widowed 4.33; 1.32-14.25) compared those married. 3.78; 1.20-11.93) 20.78; 2.94-141.2) reported 5 more lifetime sexual partners at most 1 partner. For there an increased receiving increasing numbers injections 6 months prior (p < 0.001 for trend). Women reporting sex against will year 7.84; 1.29-47.86; p = 0.020). The strongest factor this is partners. risks found coercive require further investigation. (authors)