Visceral adiposity index is associated with increased urinary albumin excretion: A population-based study.

摘要: Summary Background The effects of visceral fat accumulation on the renal damage have drawn much attention. We aimed to investigate possible relationship between adiposity and albuminuria. Methods included information from a population-based study in 9473 subjects aged 40 years or older. As novel valid indicator for adipose function, index (VAI) was determined by gender-specific equations calculated using simple anthropometric functional parameters. Increased urinary albumin excretion defined as albumin-to-creatinine ratio (ACR) 30 mg/g greater. Results prevalence rate increased 6.6% this population gradually across VAI quartiles. Participants with higher had elevated age, blood pressure, cholesterol, fasting insulin decreased high density lipoprotein cholesterol estimated glomerular filtration (eGFR) level. In multivariate logistic regression analysis, adjusted odds ratios (ORs) increasing quartiles were 1.00 (reference), 1.29 (95% confidence intervals [CI] 0.94–1.76), 1.46 CI 1.08–1.97) 1.79 1.33–2.41). subgroup analysis after multiple adjustments, significant relation level prevalent detected women, younger subjects, non-obesity those without diabetes eGFR ≥60 ml/min per 1.73 m2. Conclusion Visceral evaluating is independently associated middle-aged elderly Chinese.