An enantioselective process for the preparation of chiral triaryl derivatives and chiral intermediates for use therein

摘要: An enantioselective multi-stage process is described which uses as a starting material an α,β-unsaturated olefin of the formula (1): Ar-CH=C(R4)COAux, where Ar and R4, may be same or different, each monocyclic bicyclic aryl group optionally containing one more heteroatoms selected from oxygen, sulphur nitrogen atoms; Aux residue chiral (R- S-) auxiliary. In process, converted to triarylethane are useful PDE IV inhibitors.