Alkyne as a spectator ligand for the nickel-catalyzed multicomponent connection reaction of diphenylzinc, 1,3-butadiene, aldehydes, and amines.

作者: Masanari Kimura , Yasushi Tatsuyama , Keisuke Kojima , Yoshinao Tamaru

DOI: 10.1021/OL0703480

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摘要: Under nickel catalysis, in the presence of 3-hexyne, aldimines aromatic amines react with Ph2Zn and one molecule butadiene to provide 1 exclusively, while aliphatic two molecules 2 where 3-hexyne serves as a spectator ligand controlling selective formation 2.

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