Microreactors as Tools for Synthetic Chemists—The Chemists' Round‐Bottomed Flask of the 21st Century?

作者: Karolin Geyer , Jeroen D. C. Codée , Peter H. Seeberger

DOI: 10.1002/CHEM.200600596

关键词:

摘要: Will microreactors replace the round-bottomed flask to perform chemical reactions in near future? Recent developments construction of microstructured reaction devices and their wide-ranging applications many different areas chemistry suggest that they can have a significant impact on way chemists conduct experiments. Miniaturizing offers advantages for synthetic organic chemist: high-throughput scanning conditions, precise control variables, use small quantities reagents, increased safety parameters, ready scale-up procedures. A wide range single- multiphase now been performed microfluidic-based devices. Certainly, cannot be applied all chemistries yet microfluidic systems also disadvantages. Limited reaction-time range, high sensitivity precipitating products, new physical, chemical, analytical challenges overcome. This concept article presents an overview available synthesis evaluates potential microreactor technology synthesis.

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