Is parity associated with earlier diagnosis of type 2 diabetes

摘要: Abstract Aim : Whether parity promotes the development of diabetes has been a subject controversy. Earlier population studies have produced discrepant findings. The aim current study was to investigate this question by examining relationship between and age diagnosis diabetes. Methods: A retrospective analysis from database conducted. Data for 2102 women with type 2 (T2DM), including date birth, at diagnosis, parity, body mass index (BMI), family history were extracted. multivariate linear regression model applied ascertain if there an association Results: With correction year significant ( β =−0.25±0.08, P = 0.002, where is coefficient). That is, increase in one, decreased 0.25 years. When further adjustments made other variables data set, effect on overall cohort disappeared, but it persisted subjects born before 1950 =−0.17±0.1, 0.09), or >5 =−0.60±0.25, 0.02). Conclusions: There diabetes, suggesting that pregnancy may promote However, magnitude small, unlikely be great clinical significance society today.