Lipid Clearing in Premature Infants during Continuous Heparin Infusion: Role of Circulating Lipases

摘要: The nature of the lipases released into circulation during low level continuous infusion heparin (1 unit/ml total parenteral nutrition) and after bolus injection (10 units/kg) was investigated in a group 11 birth weight infants (gestational age 27-34 wk, postnatal 7-26 days) receiving nutrition with Intralipid (0.5 g/kg). Hepatic lipase extra-hepatic lipoprotein were differentiated aid an antibody specific for human hepatic lipase. data show that leads to constant baseline postheparin lipolytic activity 0.77 +/- 0.18 mumol free fatty acids per milliliter serum hour. Bolus peak levels 3.77 0.46 hour, 10 min injection. About two-thirds type or heparin.