Factors associated with variability in retinal nerve fiber layer thickness measurements obtained by optical coherence tomography.

摘要: Objective To identify factors associated with variability in retinal nerve fiber layer (RNFL) thickness measurements obtained by optical coherence tomography (OCT). Design Retrospective observational case series. Participants One hundred fifty consecutive patients known or suspected glaucomatous optic damage undergoing OCT imaging for RNFL measurement. Methods eye glaucoma from each patient was scanned twice within the same visit using Stratus OCT's fast acquisition protocol. For scan, average thickness, signal strength (a measure of amount light reflecting back retina), and analysis confidence (AC, a quality data as reported software) were recorded. Retinal initial repeat scans compared, difference correlated strength, AC (either low normal), thickness. Main Outcome Measure Difference Results The mean between 10 microns (12.5%; range, 0.04–86.15 microns). positively (Spearman correlation coefficient=0.44; P = 0.002). presence scan lower greater scans. Conclusions Signal variability, AC, are OCT. Comparability visits may be improved if similar strengths without obtained. This is especially important moderate whom good not obtainable.