Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus
作者： Xiaodong Li , Frédéric Gaillard , Elizabeth A. Monckton , Darryl D. Glubrecht , Amit R. L. Persad
DOI: 10.1186/S13041-016-0244-0
关键词:
摘要: Background AP-2δ is the most divergent member of Activating Protein-2 (TFAP2) family transcription factors. AP-2δ restricted to specific regions CNS, including a subset ganglion cells in retina. Retinal (RGCs), only output neurons retina, are responsible for transmitting visual signal brain.
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