Effects of the pulsed electromagnetic field PST® on human tendon stem cells: a controlled laboratory study.

摘要: Current clinical procedures for rotator cuff tears need to be improved, as a high rate of failure is still observed. Therefore, new approaches have been attempted stimulate self-regeneration, including biophysical stimulation modalities, such low-frequency pulsed electromagnetic fields, which are alternative and non-invasive methods that seem produce satisfying therapeutic effects. While little known about their mechanism action, it has speculated they may act on resident stem cells. Thus, the purpose this study was evaluate effects field (PST®) human tendon cells (hTSCs) in order elucidate possible observed hTSCs from were isolated biopsies cultured vitro. Then, exposed 1-h PST® treatment compared control untreated terms cell morphology, proliferation, viability, migration, marker expression. Exposure did not cause any significant changes morphology. Instead, while expression significantly decreased during culturing, PST®-treated reduction same markers. had beneficial expression, treated maintained higher these markers culturing. These results support notion increase patient regenerative potential.