Recent progress in studies of the transdifferentiation of eye tissue in vitro

摘要: A major switch in the overt differentiation phenotypes, which we call transdifferentiation, occurs very often cultures of embryonic eye tissues. The systems provide irrevocable evidence for instability results cell differentiation, and hence, studies on this topic are expected to contribute much understanding basic mechanisms differentiation. In article, recent work mostly with chick embryos, was reviewed. Several new lens transdifferentiation starting from brains, adenohypophyses, other tissues have recently been discovered. Regarding widely known cases neural pigmented retina cells, there has considerable progress elucidating factors controlling such switches particular, efforts under way attempt understand relation transcriptional control genes coding lens-specific proteins.