A prospective randomized multicenter comparison on health-related quality of life: the value of add-on arrhythmia surgery in patients with paroxysmal, permanent or persistent atrial fibrillation undergoing valvular and/or coronary bypass surgery.

摘要: Quality of Life After Add-on Arrhythmia Surgery Introduction: This is a multicenter, prospective, randomized controlled trial to determine the effect add-on arrhythmia surgery on health-related quality life during 1-year follow-up cardiac patients with atrial fibrillation. Methods: 150 documented fibrillation were randomly assigned undergo or without surgery. Patients completed questionnaires, comprising RAND 36-item Health Survey 1.0 (SF-36), Multidimensional Fatigue Inventory-20 (MFI-20) and EuroQoL (EQ-5D VAS) at baseline 3, 6, 12 months following operation. Results: 132 questionnaires minimum one time-point follow-up. At patient characteristics, operative data comparable. 12-month 62 free significant differences between groups (P = 0.28). Conversion SR occurred in 69.8% (37/53) paroxysmal AF, 28.2% (11/39) permanent AF 44.4% (12/27) persistent AF. Cardiac general resulted an overall improvement SF-36 MFI-20. However, EQ-5D showed deterioration subscale Pain/Discomfort for both < 0.001), worse outcome control group 0.006). Conclusions: Health-related paroxysmal, improves after regardless giving not, but this presumably more affected by treating underlying heart disease than restoring sinus rhythm. (J Cardiovasc Electrophysiol, Vol. 21, pp. 511-520, May 2010)