Predictors of Lung Transplant Survival in Eurotransplant

摘要: This study was undertaken to assess the influence of patient/donor and center factors on lung transplantation outcome. Outcomes all consecutive first cadaveric transplants performed at 21 Eurotransplant centers in 1997–99 were analyzed. The risk-adjusted effect mortality estimated. A Cox model built including donor recipient age gender, primary disease, HLA mismatches, patient's residence, cold ischemic time, donor's cause death, serum creatinine, type transplant, respiratory support status, clinical condition percentage predicted FEV1. calculated (expressed as standardized difference between observed expected survival rates), empirical full Bayes methods applied evaluate between-center differences. total 590 adults underwent transplantation. disease (p=0.01), HLA-mismatches (p = 0.02), condition(p < 0.0001) status 0.05) significantly associated with survival. After adjusting for case-mix, no differences could be found. An in-depth analysis showed variation zero. Similar results obtained from analysis. Based these data, there is scientific basis a hypothesis possible association volume rates.