G-Protein-Linked Receptors and Tyrosine Kinase-Mediated Signal Transduction Pathways: A Mid-1990s Perspective, with Working Hypotheses
DOI: 10.1007/978-3-0348-7218-8_9
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摘要: G-protein signalling paradigms are reviewed, and data coming from four laboratories summarized, indicating that G-protein-coupled agonists may act via tyrosine kinase pathways. Approaches to the analysis of these putative G-protein-regulated pathways outlined working hypotheses put forward explain link between serpentine receptors such as ones for angiotensin-II, vasopressin bombesin activation kinases P125FAK.
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