Histopathology of colorectal carcinomas and adenomas in cancer family syndrome

摘要: Seventy-five colorectal carcinoma patients (100 separate cancers) with verified cancer family syndrome were re-examined for the evaluation of histologic characteristics in carcinomas and adenomatous polyps this inherited a comparison control but no hereditary background. In group there significantly more mucinous (35 to 39 percent vs. 20 percent;P<0.05–0.01), also poorly differentiated tumors (24 12 percent) than group. The differences could not be explained by site or stage age sex patients. Additional adenomas occurred quite often both (19 controls (16 percent). group, however, moderate severe dysplasia (P<0.01) villous features (P<0.05) Mucinous carcinoma, although fully specific, might characteristic syndrome, thus serve as one sign indentification syndrome. presence adenoma-carcinoma sequence was supported, aggressivity associated signify an accelerated advancement phenomenon