Ability of Thymosin to Decrease in Vivo and in Vitro Suppressor Cell Activity in Tumor Bearing Mice and Cancer Patients

摘要: We have demonstrated that splenic lymphocytes from normal syngeneic animals can stimulate tumor growth. This effect is T-cell dependent. Preincubation of these with thymosin not only blocks facilitated growth but induce a significant reduction local and number pulmonary metastases. Furthermore, also block the expression suppressor activity either stimulated by Con A or originating various advanced solid bearing patients. These results therefore suggest able to modulate, directly indirectly, functional cells.