Determination of polymorphisms using isothermal nucleic acid amplification

作者: Niall A. Armes , Matthew Simon Forrest

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摘要: This invention relates to methods and compositions for detecting a polymorphism in target nucleic acid sequence using isothermal amplification. More specifically, the present recombinase polymerase amplification (RPA) or Nicking Extension Amplification Reaction (NEAR) detect single nucleotide polymorphisms sequence.

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