The metabolic response of Saccharomyces cerevisiae to continuous heat stress.

摘要: A study has been initiated to integrate molecular and physiological responses of Saccharomyces cerevisiae heat stress conditions. We focus our research on a quantification the energetics response. series continuous stresses was applied exponentially growing cells strain X2180-1A at 28°C, by increasing growth temperature 37, 39, 40, 41, 42, or 43°C. Here, results cell viability, as well anabolic catabolic rates are presented. observed surprisingly ‘thin line’ for between growing, surviving, dying, with regard temperature. The showed dual effect catabolism: immediately after increase strong peak seen, which new, steady level reached. In addition, yield glucose decreased Our indicate that life elevated temperatures is energetically unfavourable non-lethal invokes redistribution fluxes.