Natural history, reasons for, and impact of low/non-adherence to medications for osteoporosis in a cohort of community-dwelling older women already established on medication: a 2-year follow-up study.

摘要: Approximately 15 % of older women on oral medications for osteoporosis could be considered alternatives including parenteral therapies. Collection data socio-demographic/clinical variables is unlikely to helpful in predicting low/non-adherence. Alternative approaches are needed identify individuals at risk This study aims individual patient reasons stopping osteoporosis, and investigate whether this can predicted from knowledge about data, or alternative need used. The Cohort Skeletal Health Bristol Avon (COSHIBA) recruited 3200 South West UK, whom a proportion were baseline. Information self-reported adherence low/non-adherence collected 6-monthly intervals over 2-year period. Data was also potential predictors impact Two hundred thirty-three (7.3 %) Mean length time treatment prior enrolment 46 months. Of those medications, 94.9 % bisphosphonates; 8.5 % reported low 21.6 % stopped their medication completely the follow-up Length baseline did not influence rates Reasons bisphosphonates included side effects (53.9 %), practical such as forgetting take them (18.0 %) beliefs (20.5 %). No convincing identified. has important implications healthcare provision. medications.