Utilization of Nuclear Matrix Proteins for Cancer Diagnosis

摘要: Abstract Circulating tumor markers have been used increasingly in recent years as clinical tools for cancer diagnosis and management. This review presents a brief discussion of currently available tumor-associated antigens. Included is an overview different functional classes circulating their applications. The limitations some traditional presently widespread use are discussed the context properties exhibited by ideal marker. nuclear matrix provides structural support nucleus plays dynamic role spatial organization genome control DNA replication transcription. recovery increased amounts specific proteins several cancers has led to further study these new class markers. Progress on protein known NuMA marker bladder presented, including results recently completed multisite trial. Additional studies potential utility prostate also presented. Nuclear could provide development assays with efficacy treatment cancer.