The Neurospora crassa cmd, trm-9, and nca-2 Genes Play a Role in Growth, Development, and Survival in Stress conditions

作者: Tamuli Ranjan

DOI: 10.5376/GAB.2015.06.0007

关键词:

摘要: The calmodulin protein antagonists, trifluoperazine (TFP) and chlorpromazine (CPZ) inhibit the growth, carotenoids accumulation sexual development of Neurospora crassa . In addition, N. strains lacking trm -9, a cation-ATPase, showed defect in growth. Moreover, both trm-9 another Ca 2+ -ATPase nca- 2, exhibited severe growth defect, an increased sensitivity to CaCl 2 , reduction acquisition thermotolerance induced by heat shock temperature. Therefore, cmd, nca -2 play role survival calcium stress temperature

参考文章(45)
Rowland H. Davis, Frederick J. de Serres, [4] Genetic and microbiological research techniques for Neurospora crassa Methods in Enzymology. ,vol. 17, pp. 79- 143 ,(1970) , 10.1016/0076-6879(71)17168-6
J A Cox, C Ferraz, J G Demaille, R O Perez, D van Tuinen, D Marmé, Calmodulin from neurospora crassa. General properties and conformational changes. Journal of Biological Chemistry. ,vol. 257, pp. 10694- 10700 ,(1982) , 10.1016/S0021-9258(18)33878-X
A. P. Carvalho, M. C. F. Lopes, M. G. P. Vale, Ca2(+)-dependent binding of tamoxifen to calmodulin isolated from bovine brain. Cancer Research. ,vol. 50, pp. 2753- 2758 ,(1990)
Hideaki Nakashima, Satoshi Katagiri, Sakura Suzuki, Mutants with altered sensitivity to a calmodulin antagonist affect the circadian clock in Neurospora crassa. Genetics. ,vol. 143, pp. 1175- 1180 ,(1996) , 10.1093/GENETICS/143.3.1175
K. McCluskey, A. Wiest, M. Plamann, The Fungal Genetics Stock Center: a repository for 50 years of fungal genetics research Journal of Biosciences. ,vol. 35, pp. 119- 126 ,(2010) , 10.1007/S12038-010-0014-6
Barry J. Bowman, Marija Draskovic, Michael Freitag, Emma Jean Bowman, Structure and distribution of organelles and cellular location of calcium transporters in Neurospora crassa Eukaryotic Cell. ,vol. 8, pp. 1845- 1855 ,(2009) , 10.1128/EC.00174-09
J J Blum, A Hayes, G A Jamieson, T C Vanaman, Calmodulin confers calcium sensitivity on ciliary dynein ATPase. Journal of Cell Biology. ,vol. 87, pp. 386- 397 ,(1980) , 10.1083/JCB.87.2.386