Histological grading in the deep invasive front of T1 and T2 glottic squamous cell carcinomas has high prognostic value.

摘要: The characteristics of the deep invasive front area squamous cell carcinomas may reflect tumour prognosis better than other parts tumour. Consequently, authors have recently developed a simple malignancy grading system based solely on oral carcinomas, which has great prognostic value. Our previous materials were somewhat heterogeneous, and value our needed to be confirmed in homogeneous patient material. In present study 95 T1−2/N0 glottic all treated by radiation, high for biopsy specimens is confirmed. significantly predicted local recurrence, i.e. treatment failure (P=0.001). Histological proved indicator T-category (size tumour), findings selection treatment. Of individual variables (pattern invasion, degree keratinization, nuclear polymorphism host response), pattern invasion keratinization strongest prognosticators multivariate analyses. Invasive also prove cancers.