Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage

作者: Frank M. LaFerla , Chiho Hirata-Fukae , Illana Gozes , Paul S. Aisen , Mark P. Mattson

DOI: 10.1385/JMN/31:02:165

关键词:

摘要: … NAP (Asn-Ala-Pro-Val-Ser-Ile-Pro-Gln) is an octapeptide that has shown … of age, and sacrificed at 12 mo of age. Although no Aβ plaque is observed in any brain region at 9 mo of age in …

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