Serotonin receptors: Therapeutic prospects in cardiovascular disease
作者： Helen E. Connor , Patrick P.A. Humphrey , Wasyl Feniuk
DOI: 10.1016/1050-1738(91)90039-H
关键词:
摘要: Serotonin is widely distributed throughout the body, can have potent and profound effects on cardiovascular system, may be involved in pathophysiology of several disease states. Recent advances classification serotonin receptors, along with identification selective drug tools for some these receptor types, enables putative role different subtypes both etiology treatment states to explored. This review considers potential therapeutic application agonists antagonists disease.
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Marion J Perren, Helen E Connor, Alexander W Oxford, Wasyl Feniuk, Patrick Pa Humphrey, The pharmacology of the novel 5-HT1-like receptor agonist, GR43175. Cephalalgia. ,vol. 9, pp. 23- 33 ,(1989) , 10.1111/J.1468-2982.1989.TB00069.X
P Schoeffter, D Hoyer, 5-Hydroxytryptamine (5-HT)-induced endothelium-dependent relaxation of pig coronary arteries is mediated by 5-HT receptors similar to the 5-HT1D receptor subtype. Journal of Pharmacology and Experimental Therapeutics. ,vol. 252, pp. 387- 395 ,(1990)
S Kalsner, R Richards, Coronary arteries of cardiac patients are hyperreactive and contain stores of amines: a mechanism for coronary spasm Science. ,vol. 223, pp. 1435- 1437 ,(1984) , 10.1126/SCIENCE.6701530
GC Scroop, JA Walsh, Interactions between angiotensin, noradrenaline and serotonin on the peripheral blood vessels in man. Immunology and Cell Biology. ,vol. 46, pp. 573- 580 ,(1968) , 10.1038/ICB.1968.164
AK Scott, P. Roy-Chaudhury, J. Webster, JC Petrie, Does a selective 5-hydroxytryptamine antagonist (ICI 169, 369) lower blood pressure in hypertensive patients? British Journal of Clinical Pharmacology. ,vol. 27, pp. 417- 421 ,(1989) , 10.1111/J.1365-2125.1989.TB05388.X
I W Reimann, J C Frolich, Mechanism of antihypertensive action of ketanserin in man. BMJ. ,vol. 287, pp. 381- 383 ,(1983) , 10.1136/BMJ.287.6389.381-A
F. B. M. Ensink, , Subcutaneous sumatriptan in the acute treatment of migraine Journal of Neurology. ,vol. 238, ,(1991) , 10.1007/BF01642910
P VIT, P DONATSCH, G ENGEL, B RICHARDSON, Inhibition of noradrenaline (NA)-induced cardiac arrhythmias in the rat by ICS 205–930 Journal of Molecular and Cellular Cardiology. ,vol. 16, pp. 25- 25 ,(1984) , 10.1016/S0022-2828(84)80430-7
Gerald J. Blauw, Peter van Brummelen, Pieter A. van Zwieten, Serotonin induced vasodilatation in the human forearm is antagonized by the selective 5-HT3 receptor antagonist ICS 205-930. Life Sciences. ,vol. 43, pp. 1441- 1449 ,(1988) , 10.1016/0024-3205(88)90255-X
G. R. Martin, P. Leff, D. Cambridge, V. J. Barrett, Comparative analysis of two types of 5-hydroxytryptamine receptor mediating vasorelaxation: differential classification using tryptamines. Naunyn-schmiedebergs Archives of Pharmacology. ,vol. 336, pp. 365- 373 ,(1987) , 10.1007/BF00164867