Metabolomics in Cancer Biomarker Research
作者： Xiaoyan Wang , Shaoqiu Chen , Wei Jia
DOI: 10.1007/S40495-016-0074-X
关键词:
摘要: Purpose of Review As a research tool for quantitative measurement small molecule metabolites, metabolomics has been devoted to search biomarkers that can be used diagnosis and prognosis malignant tumors. The purpose this review is summarize recent literatures on metabolomic-based cancer biomarker discuss the current issues challenges in clinical applications technologies.
springer.com
sci-hub.se 参考文章(50)
Philip M Tedeschi, Nadine Johnson-Farley, Hongxia Lin, Laura M Shelton, Takushi Ooga, Gillian Mackay, Niels Van Den Broek, Joseph R Bertino, Alexei Vazquez, Quantification of folate metabolism using transient metabolic flux analysis. Cancer and Metabolism. ,vol. 3, pp. 6- 6 ,(2015) , 10.1186/S40170-015-0132-6
D Geng, D Sun, L Zhang, W Zhang, The therapy of gefitinib towards breast cancer partially through reversing breast cancer biomarker arginine. African Health Sciences. ,vol. 15, pp. 594- 597 ,(2015) , 10.4314/AHS.V15I2.36
Guoxiang Xie, Bingsen Zhou, Aihua Zhao, Yunping Qiu, Xueqing Zhao, Lana Garmire, Yurii B. Shvetsov, Herbert Yu, Yun Yen, Wei Jia, Lowered circulating aspartate is a metabolic feature of human breast cancer Oncotarget. ,vol. 6, pp. 33369- 33381 ,(2015) , 10.18632/ONCOTARGET.5409
Manish Sud, Eoin Fahy, Dawn Cotter, Kenan Azam, Ilango Vadivelu, Charles Burant, Arthur Edison, Oliver Fiehn, Richard Higashi, K. Sreekumaran Nair, Susan Sumner, Shankar Subramaniam, Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools Nucleic Acids Research. ,vol. 44, pp. 463- 470 ,(2016) , 10.1093/NAR/GKV1042
J.-H. Wang, W.-L. Chen, J.-M. Li, S.-F. Wu, T.-L. Chen, Y.-M. Zhu, W.-N. Zhang, Y. Li, Y.-P. Qiu, A.-H. Zhao, J.-Q. Mi, J. Jin, Y.-G. Wang, Q.-L. Ma, H. Huang, D.-P. Wu, Q.-R. Wang, Y. Li, X.-J. Yan, J.-S. Yan, J.-Y. Li, S. Wang, X.-J. Huang, B.-S. Wang, W. Jia, Y. Shen, Z. Chen, S.-J. Chen, Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China Proceedings of the National Academy of Sciences of the United States of America. ,vol. 110, pp. 17017- 17022 ,(2013) , 10.1073/PNAS.1315558110
Oliver D. K. Maddocks, Celia R. Berkers, Susan M. Mason, Liang Zheng, Karen Blyth, Eyal Gottlieb, Karen H. Vousden, Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells Nature. ,vol. 493, pp. 542- 546 ,(2013) , 10.1038/NATURE11743
Eun-Hee Shim, Carolina B. Livi, Dinesh Rakheja, Jubilee Tan, Daniel Benson, Vishwas Parekh, Eun-Young Kho, Arindam P. Ghosh, Richard Kirkman, Sadanan Velu, Shilpa Dutta, Balachandra Chenna, Shane L. Rea, Robert J. Mishur, Qiuhua Li, Teresa L. Johnson-Pais, Lining Guo, Sejong Bae, Shi Wei, Karen Block, Sunil Sudarshan, L-2-Hydroxyglutarate: An Epigenetic Modifier and Putative Oncometabolite in Renal Cancer Cancer Discovery. ,vol. 4, pp. 1290- 1298 ,(2014) , 10.1158/2159-8290.CD-13-0696
Yunping Qiu, Guoxiang Cai, Bingsen Zhou, Dan Li, Aihua Zhao, Guoxiang Xie, Houkai Li, Sanjun Cai, Dong Xie, Changzhi Huang, Weiting Ge, Zhanxiang Zhou, Lisa X. Xu, Weiping Jia, Shu Zheng, Yun Yen, Wei Jia, A distinct metabolic signature of human colorectal cancer with prognostic potential Clinical Cancer Research. ,vol. 20, pp. 2136- 2146 ,(2014) , 10.1158/1078-0432.CCR-13-1939
C. A. M. Van Gestel, T. C. Van Brummelen, Incorporation of the biomarker concept in ecotoxicology calls for a redefinition of terms. Ecotoxicology. ,vol. 5, pp. 217- 225 ,(1996) , 10.1007/BF00118992
Aurélie Roux, Etienne A. Thévenot, François Seguin, Marie-Françoise Olivier, Christophe Junot, Impact of collection conditions on the metabolite content of human urine samples as analyzed by liquid chromatography coupled to mass spectrometry and nuclear magnetic resonance spectroscopy Metabolomics. ,vol. 11, pp. 1095- 1105 ,(2015) , 10.1007/S11306-014-0764-5