The Extracellular Calcium-Sensing Receptor (CaSR) Is a Critical Modulator of Skeletal Development
作者： W. Chang , C. Tu , T.-H. Chen , D. Bikle , D. Shoback
DOI: 10.1126/SCISIGNAL.1159945
关键词:
摘要: … CaSR in PTCs, which was demonstrated previously in Casr −/… of Casr to skeletal development in vivo, we bred floxed Casr … ) to produce PTC-specific Casr KO mice. Heterozygous ( PT …
sciencemag.org
researchgate.net 参考文章(38)
Shoback D, Chang W, Rodriguez L, Chen Th, Tu C, Extracellular Ca2+-sensing in cartilage. Journal of Musculoskeletal & Neuronal Interactions. ,vol. 4, pp. 410- 411 ,(2004)
E.M. BROWN, The calcium-sensing receptor: physiology, pathophysiology and CaR-based therapeutics. Sub-cellular biochemistry. ,vol. 45, pp. 139- 167 ,(2007) , 10.1007/978-1-4020-6191-2_6
M. K. BERGENSTOCK, N. C. PARTRIDGE, Parathyroid hormone stimulation of noncanonical Wnt signaling in bone. Annals of the New York Academy of Sciences. ,vol. 1116, pp. 354- 359 ,(2007) , 10.1196/ANNALS.1402.047
Chrystal Ho, David A. Conner, Martin R. Pollak, Daniel J. Ladd, Olga Kifor, Henry B. Warren, Edward M. Brown, J.G. Seidman, Christine E. Seidman, A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism Nature Genetics. ,vol. 11, pp. 389- 394 ,(1995) , 10.1038/NG1295-389
C. G. BELLOWS, H. ISHIDA, J. E. AUBIN, J. N. M. HEERSCHE, Parathyroid Hormone Reversibly Suppresses the Differentiation of Osteoprogenitor Cells into Functional Osteoblasts Endocrinology. ,vol. 127, pp. 3111- 3116 ,(1990) , 10.1210/ENDO-127-6-3111
Luis Rodriguez, Zhiqiang Cheng, Tsui-Hua Chen, Chialing Tu, Wenhan Chang, Extracellular Calcium and Parathyroid Hormone- Related Peptide Signaling Modulate the Pace of Growth Plate Chondrocyte Differentiation Endocrinology. ,vol. 146, pp. 4597- 4608 ,(2005) , 10.1210/EN.2005-0437
Wenhan Chang, Dolores Shoback, Extracellular Ca2+-sensing receptors--an overview. Cell Calcium. ,vol. 35, pp. 183- 196 ,(2004) , 10.1016/J.CECA.2003.10.012
John C Huang, Takeshi Sakata, Laura L Pfleger, Margaret Bencsik, Bernard P Halloran, Daniel D Bikle, Robert A Nissenson, PTH differentially regulates expression of RANKL and OPG. Journal of Bone and Mineral Research. ,vol. 19, pp. 235- 244 ,(2003) , 10.1359/JBMR.0301226
Wenhan Chang, Chialing Tu, Stacy Pratt, Tsui-Hua Chen, Dolores Shoback, Extracellular Ca2+-Sensing Receptors Modulate Matrix Production and Mineralization in Chondrogenic RCJ3.1C5.18 Cells Endocrinology. ,vol. 143, pp. 1467- 1474 ,(2002) , 10.1210/ENDO.143.4.8709
Y. Maeda, E. Nakamura, M.-T. Nguyen, L. J. Suva, F. L. Swain, M. S. Razzaque, S. Mackem, B. Lanske, Indian hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 6382- 6387 ,(2007) , 10.1073/PNAS.0608449104