Cortical network from human embryonic stem cells.
作者： Roxana Nat
DOI: 10.1111/J.1582-4934.2011.01309.X
关键词:
摘要: The connection of embryonic stem cell technology and developmental biology provides valuable tools to decipher the mechanisms underlying human brain development diseases, especially among neuronal populations, that are not readily available in primary cultures. It is obviously case neurons forming cerebral cortex. In images presented, were generated vitro from cells via forebrain-like progenitors. Maintained culture for prolonged time, they acquired a mainly glutamatergic phenotype morphological characteristics cortical pyramidal neurons, including dendritic spines, formed spectacular networks.
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