Hepatitis E virus strains infecting Swedish domestic pigs are unique for each pig farm and remain in the farm for at least 2 years.

摘要: Hepatitis E virus (HEV) genotype 3 (HEV3) is distributed globally and infects both humans animals, mainly domestic pigs wild boars, which are the major reservoirs. In this study, prevalence of HEV among Swedish was investigated by RNA analysis in 363 faecal samples from 3-month-old piglets sampled twice (2013 2014) 30 pig farms. Four different types farms were investigated; organic, conventional closed (keeping sow), satellites a sow pool (conventional sharing sows) non-closed (purchasing gilts). More than two-thirds (77%) had HEV-infected pigs. found faeces 79 (22%). Partial ORF1 could be sequenced 46 strains. Phylogenetic revealed unique HEV3 strain for each farm. Strains more year apart same farm closely related, indicating that present several years on Despite only 4% investigated, two strains similar to those humans, another boar HEV. The uniqueness indicates possibility identify source infection down level. This knowledge may used investigate effectiveness good hygiene routines reduce amount thus risk farm, public health authorities cases transmissions consumption uncooked pork.