Hepatitis E virus genotype 3 strains and a plethora of other viruses detected in raw and still in tap water

摘要: Abstract In this study, next generation sequencing was used to explore the virome in 20L up 10,000L water from different purification steps at two Swedish drinking treatment plants (DWTPs), and tap water. One DWTP ultrafiltration (UF) with 20 nm pores, other UV light after conventional of Viruses belonging 26 families were detected raw water, which 6–9 times more sequence reads found for phages than known environmental, plant or vertebrate viruses. The total number viral reduced 4-log10 UF 3-log10 over treatment. However, some viruses reduction 3.5-log10 UF, as hepatitis E virus (HEV), also sequences similar those This indicates that HEV had passed through entered into supply network. viability is unknown. 10–130 International Units RNA/mL identified, a comparable low amount virus. risk getting infected consumption probably negligible, but needs be investigated. strains waters belonged subtypes HEV3a HEV3c/i, associated unknown source infection humans Sweden. None these are common among pigs wild boar, major reservoirs HEV, indicating may play role transmitting results indicate monitoring small fecal/oral transmitted DWTPs considered, especially during community outbreaks, prevent potential transmission by