Handling of radical prostatectomy specimens: total or partial embedding?

摘要: Vainer B, Toft B G, Olsen K E, Jacobsen G & Marcussen N (2011) Histopathology58, 211–216 Handling of radical prostatectomy specimens: total or partial embedding? Aims:  Proper examination and accurate reporting specimens (RPS) is essential in determining post-surgical treatment predicting patient outcome. Surveys have demonstrated the absence consensus on handling RPS. The aim this study was to determine whether significant information lost when only half horizontal tissue sections are examined. Methods results:  During a 1-year period, 238 RPS were sectioned into slices. Apex basis cut sagittally, remaining slices embedded quadrants. Glass slides from every second slice withheld. evaluated microscopically, pathological parameters recorded. Subsequently, full report compiled, including withheld slides. A median 12 (30%) during initial assessment. In eight (3.2%) pTNM stage had be changed; six cases (2.6%) pT2b pT2c two (0.8%) pT3a. one (0.4%) surgical margin status changed. Conclusions:  Only little with systematic embedding, overlooking features for postoperative 1.2%. Partial embedding as suggested, decreasing laboratory workload by 30%, concluded acceptable valid histopathological