Handling and reporting of radical prostatectomy specimens in Europe: a web-based survey by the European Network of Uropathology (ENUP)

作者: L Egevad , F Algaba , D M Berney , L Boccon-Gibod , D F Griffiths

DOI: 10.1111/J.1365-2559.2008.03102.X

关键词:

摘要: Aims:  To survey current European practices in handling and reporting of radical prostatectomy (RP) specimens. Methods results:  A Network Uropathology (ENUP) was organized for the dissemination information, studies research collaborations. Contact data uropathologists were collected from 321 pathology laboratories 15 West countries. In first ENUP survey, 67.6% (217/321) members replied to a web-based questionnaire. Some adopted by large majority, e.g. inking specimen (96.6%), Gleason grading (99.5%), stratifying extraprostatic extension (EPE) according extent (88.2%), TNM stage (88.6%) location positive margins (98%). As many as 71.6% respondents always embedded entire prostate only 10.8% practised partial embedding. Whole mounts routinely used 37.5% standard blocks 55.5%. Among areas with variable routines methods define focal versus extensive EPE quantify margin positivity, probably reflecting that optimal method has yet be determined. Conclusions:  are almost universally Europe, whereas others still need standardized. The results study may helpful when judging what recommendations reasonable issue.

参考文章(19)
Lars Egevad, William C. Allsbrook, Jonathan I. Epstein, Current practice of diagnosis and reporting of prostate cancer on needle biopsy among genitourinary pathologists Human Pathology. ,vol. 37, pp. 292- 297 ,(2006) , 10.1016/J.HUMPATH.2005.10.011
Lars Egevad, William C. Allsbrook, Jonathan I. Epstein, Current practice of Gleason grading among genitourinary pathologists Human Pathology. ,vol. 36, pp. 5- 9 ,(2005) , 10.1016/J.HUMPATH.2004.10.001
André N. Vis, Fritz H. Schröder, Theodorus H. van der Kwast, The Actual Value of the Surgical Margin Status as a Predictor of Disease Progression in Men with Early Prostate Cancer European Urology. ,vol. 50, pp. 258- 265 ,(2006) , 10.1016/J.EURURO.2005.11.030
EIJI KIKUCHI, PETER T. SCARDINO, THOMAS M. WHEELER, KEVIN M. SLAWIN, MAKOTO OHORI, Is tumor volume an independent prognostic factor in clinically localized prostate cancer The Journal of Urology. ,vol. 172, pp. 508- 511 ,(2004) , 10.1097/01.JU.0000130481.04082.1A
Thomas M Wheeler, Özdal Dillioglugil, Michael W Kattan, Atsushi Arakawa, Shigehiro Soh, Kazuho Suyama, Makoto Ohori, Peter T Scardino, None, Clinical and pathological significance of the level and extent of capsular invasion in clinical stage T1-2 prostate cancer. Human Pathology. ,vol. 29, pp. 856- 862 ,(1998) , 10.1016/S0046-8177(98)90457-9
Sara Jonmarker, Alexander Valdman, Anna Lindberg, Magnus Hellström, Lars Egevad, Tissue shrinkage after fixation with formalin injection of prostatectomy specimens. Virchows Archiv. ,vol. 449, pp. 297- 301 ,(2006) , 10.1007/S00428-006-0259-5
Vernon E. Weldon, Frank R. Tavel, H. Neuwirth, R. Cohen, Patterns of Positive Specimen Margins and Detectable Prostate Specific Antigen After Radical Perineal Prostatectomy The Journal of Urology. ,vol. 153, pp. 1565- 1569 ,(1995) , 10.1016/S0022-5347(01)67462-7
Roger B. Watson, Francisco Civantos, Mark S. Soloway, Positive surgical margins with radical prostatectomy: detailed pathological analysis and prognosis Urology. ,vol. 48, pp. 80- 90 ,(1996) , 10.1016/S0090-4295(96)00092-1