Impact of the CHA2DS2-VASc Score on Anticoagulation Recommendations for Atrial Fibrillation

作者: Pamela K. Mason , Douglas E. Lake , John P. DiMarco , John D. Ferguson , J. Michael Mangrum

DOI: 10.1016/J.AMJMED.2011.09.030

关键词:

摘要: Abstract Background The Congestive heart failure, Hypertension, Age≥75 years, Diabetes mellitus, Stroke (CHADS 2 ) score is used to predict the need for oral anticoagulation stroke prophylaxis in patients with atrial fibrillation. Stroke, Vascular disease, Age 65-74 Sex category (CHA DS -VASc) schema has been proposed as an improvement. Our objective determine how adoption of CHA -VASc alters recommendations. Methods Between 2004 and 2008, 1664 were seen at University Virginia Atrial Fibrillation Center. We calculated CHADS scores each patient. 2006 American College Cardiology/American Heart Association/Heart Rhythm Society guidelines fibrillation management recommendations based on score, 2010 European Cardiology score. Results average age was 62±13 34% women. Average 1.1±1.1 1.8±1.5, respectively ( P 0001). classified 33% requiring anticoagulation. 53% For women, 31% had a score≥2, but 81% score≥2 = . Also, 32% women zero score≥2. men, 25% 39% Conclusion Compared more clearly defines Many patients, particularly older are redistributed from low- high-risk categories.

参考文章(22)
G Neal Kay, Juan L Tamargo, Jonathan L Halperin, Anne B Curtis, S Bertil Olsson, Valentín Fuster, Samuel Wann, David S Cannom, Jean-Yves Le Heuzey, Eric N Prystowsky, Lars E Rydén, Harry J Crijns, Kenneth A Ellenbogen, James E Lowe, Guidelines for the management of patients with atrial fibrillation. Executive summary Revista Espanola De Cardiologia. ,vol. 59, pp. 1329- ,(2006)
Emelia J Benjamin, Daniel Levy, Sonya M Vaziri, Ralph B D'Agostino, Albert J Belanger, Philip A Wolf, Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study. JAMA. ,vol. 271, pp. 840- 844 ,(1994) , 10.1001/JAMA.1994.03510350050036
Margaret C Fang, Alan S Go, Yuchiao Chang, Leila Borowsky, Niela K Pomernacki, Daniel E Singer, ATRIA Study Group, Comparison of Risk Stratification Schemes to Predict Thromboembolism in People With Nonvalvular Atrial Fibrillation Journal of the American College of Cardiology. ,vol. 51, pp. 810- 815 ,(2008) , 10.1016/J.JACC.2007.09.065
Nicole L Glazer, Sascha Dublin, Nicholas L Smith, Benjamin French, Lisa A Jackson, Jennifer B Hrachovec, David S Siscovick, Bruce M Psaty, Susan R Heckbert, None, Newly Detected Atrial Fibrillation and Compliance With Antithrombotic Guidelines JAMA Internal Medicine. ,vol. 167, pp. 246- 252 ,(2007) , 10.1001/ARCHINTE.167.3.246
Brian F. Gage, Amy D. Waterman, William Shannon, Michael Boechler, Michael W. Rich, Martha J. Radford, Validation of Clinical Classification Schemes for Predicting Stroke JAMA. ,vol. 285, pp. 2864- 2870 ,(2001) , 10.1001/JAMA.285.22.2864
R. Nieuwlaat, A. Capucci, G. Y.H. Lip, S. B. Olsson, M. H. Prins, F. H. Nieman, J. Lopez-Sendon, P. E. Vardas, E. Aliot, M. Santini, H. J.G.M. Crijns, , Antithrombotic treatment in real-life atrial fibrillation patients: a report from the Euro Heart Survey on Atrial Fibrillation. European Heart Journal. ,vol. 27, pp. 3018- 3026 ,(2006) , 10.1093/EURHEARTJ/EHL015
Henry S. Cabin, K.Soni Clubb, Cynthia Hall, Robin A. Perlmutter, Alvan R. Feinstein, Risk for systemic embolization of atrial fibrillation without mitral stenosis The American Journal of Cardiology. ,vol. 65, pp. 1112- 1116 ,(1990) , 10.1016/0002-9149(90)90323-S
Peter J. Zimetbaum, Amit Thosani, Hsing-Ting Yu, Yan Xiong, Jay Lin, Prajesh Kothawala, Matthew Emons, Are Atrial Fibrillation Patients Receiving Warfarin in Accordance with Stroke Risk The American Journal of Medicine. ,vol. 123, pp. 446- 453 ,(2010) , 10.1016/J.AMJMED.2009.11.015
Michael Broukhim, Jonathan L. Halperin, Stroke Prevention in the High-risk Atrial Fibrillation Patient: Medical Management Current Cardiology Reports. ,vol. 13, pp. 9- 17 ,(2011) , 10.1007/S11886-010-0148-Z