Stable apomorphine composition and uses thereof

作者: Ahamad Malkawi , Abeer M. Al-Ghananeem

DOI:

关键词:

摘要: This application relates to a stable liquid aqueous formulations comprising at least about 10 mg/ml of apomorphine hydrochloride hemihydrate (apomorphine HQ), which are substantially free antioxidant agents, such as sodium metabisulfite. formulation is designed improve patient tolerance and compliance, while the same time maintaining stability pharmaceutical formulation. These may be used in treatment and/or management advanced cases Parkinson's disease.

参考文章(3)
Ahmad Malkawi, George A. Digenis, Abeer M. Al-Ghananeem, Patrick Deluca, Co-solvent compositions and methods for improved delivery of dantrolene therapeutic agents ,(2008)
Paolo Chiesi, Gaetano Brambilla, Eva Bernini, Stable apomorphine solution formulations ,(1999)