Neuroprotection by pharmacologic blockade of the GAPDH death cascade

作者: M. R. Hara , B. Thomas , M. B. Cascio , B.-I. Bae , L. D. Hester

DOI: 10.1073/PNAS.0511321103

关键词:

摘要: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) participates in a cell death cascade wherein a variety of stimuli activate nitric oxide (NO) synthases with NO nitrosylating GAPDH…

参考文章(28)
P. C. Waldmeier, A. A. Boulton, A. R. Cools, A. C. Kato, W. G. Tatton, Neurorescuing effects of the GAPDH ligand CGP 3466B. Journal of Neural Transmission-supplement. pp. 197- 214 ,(2000) , 10.1007/978-3-7091-6301-6_13
Samie R. Jaffrey, Hediye Erdjument-Bromage, Christopher D. Ferris, Paul Tempst, Solomon H. Snyder, Protein S-nitrosylation: a physiological signal for neuronal nitric oxide. Nature Cell Biology. ,vol. 3, pp. 193- 197 ,(2001) , 10.1038/35055104
Allen S. Mandir, Cynthia M. Simbulan-Rosenthal, Marc F. Poitras, John R. Lumpkin, Valina L. Dawson, Mark E. Smulson, Ted M. Dawson, A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism. Journal of Neurochemistry. ,vol. 83, pp. 186- 192 ,(2002) , 10.1046/J.1471-4159.2002.01144.X
Graeme W. Carlile, Nadine A. Tatton, Ruth M. E. Chalmers-Redman, Katherine L.B. Borden, William G. Tatton, Amanda Pong, Reduced apoptosis after nerve growth factor and serum withdrawal: conversion of tetrameric glyceraldehyde-3-phosphate dehydrogenase to a dimer. Molecular Pharmacology. ,vol. 57, pp. 2- 12 ,(2000)
Silvia Mandel, Orly Weinreb, Tamar Amit, Moussa B.H. Youdim, Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives. Brain Research Reviews. ,vol. 48, pp. 379- 387 ,(2005) , 10.1016/J.BRAINRESREV.2004.12.027
R. Ravikumar, M.K. Lakshmana, B.S. Shankaranarayana Rao, B.L. Meti, P.N. Bindu, T.R. Raju, Deprenyl Attenuates Spinal Motor Neuron Degeneration and Associated Locomotor Deficits in Rats Subjected to Spinal Cord Ischemia Experimental Neurology. ,vol. 149, pp. 123- 129 ,(1998) , 10.1006/EXNR.1997.6682
John J. Skratt, Ian Irwin, Louis E. DeLanney, J.William Langston, Kevin T. Finnegan, Protection against DSP-4-induced neurotoxicity by deprenyl is not related to its inhibition of MAO B European Journal of Pharmacology. ,vol. 184, pp. 119- 126 ,(1990) , 10.1016/0014-2999(90)90672-S
G. Andringa, R. V. Van Oosten, W. Unger, T. G. M. Hafmans, J. Veening, J. C. Stoof, A. R. Cools, Systemic administration of the propargylamine CGP 3466B prevents behavioural and morphological deficits in rats with 6-hydroxydopamine-induced lesions in the substantia nigra European Journal of Neuroscience. ,vol. 12, pp. 3033- 3043 ,(2000) , 10.1046/J.1460-9568.2000.00181.X