Sphingosine 1-phosphate receptor agonists: a patent review (2010 – 2012)
作者： Edward Roberts , Miguel Guerrero , Mariangela Urbano , Hugh Rosen
DOI: 10.1517/13543776.2013.783022
关键词:
摘要: … Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid metabolite found in lymph (30 – 300 nM) and plasma (100 nM – 1 μM) [1]. A significant fraction of lymph and plasma …
informahealthcare.com参考文章(99)
Nuria Godessart Marina, Gema Tarrason Encuentra, Nuria Aguilar Izquierdo, S1P1 receptor agonists for use in the treatment of crohn's disease ,(2010)
Alaric J. Dyckman, Recent Advances in the Discovery and Development of Sphingosine-1-Phosphate-1 Receptor Agonists Annual Reports in Medicinal Chemistry Volume 47. ,vol. 47, pp. 195- 207 ,(2012) , 10.1016/B978-0-12-396492-2.00013-8
Christopher M. Harris, Adrian D. Hobson, Noel S. Wilson, Agonists and antagonists of the s1p5 receptor, and methods of uses thereof ,(2010)
Yves Auberson, David Orain, Emmanuelle Briard, Fty720 halogenated derivatives ,(2010)
Thomas Huebschle, Katrin Hiss, Stephanie Hachtel, Axel Dietrich, Dieter Kadereit, Matthias Schaefer, Carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring ,(2011)
Haibo Zhang, Feng Ren, Xichen Lin, Pyrimidine derivatives for use as sphingosine 1-phosphate 1 (s1p1) receptor agonists ,(2011)
G protein-coupled receptors : structure, signaling, and physiology Cambridge University Press. ,(2010) , 10.1017/CBO9780511760334
Rajamannar Thennati, Bhavesh M. Panchal, Biswajit Samanta, Jeanne-Marie Lecomte, Marc Capet, Jayraj D. Aradhye, Ranjan Kumar Pal, Muthukumaran Natarajan Pillai, Isabelle Berrebi-Bertrand, Sandeep Pankajbhai Pathak, Dijixa Chandubhai Rana, Kaushik Dhanjubhai Prajapati, Jean-Charles Schwartz, Philippe Robert, Novel piperidinyl monocarboxylic acids as s1p1 receptor agonists ,(2012)
Anna Quattropani, Jerome Dorbais, Patrick Gerber, Oxazole pyridine derivatives useful as s1p1 receptor agonists ,(2010)
Thomas Huebschle, Katrin Hiss, Stephanie Hachtel, Andreas Gille, Axel Dietrich, Dieter Kadereit, Matthias Schaefer, 2,5,7-substituted oxazolopyrimidine derivatives ,(2011)