MS/MS Fragmentation Behavior Study of meso-Phenylporphyrinoids Containing Nonpyrrolic Heterocycles and meso-Thienyl-Substituted Porphyrins
作者： Ekta Mishra , Jill L. Worlinsky , Christian Brückner , Victor Ryzhov
DOI: 10.1007/S13361-013-0750-6
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摘要: Free base and cobalt(II) complexes of six meso-tetraphenylporphyrinoids containing nonpyrrolic heterocycles three meso-thienylporphyrins were investigated using electrospray ionization tandem mass spectrometry (ESI-MS/MS). Their fragmentation was studied in a quadrupole ion trap as function the porphyrinoid macrocycle structure compared with behavior benchmark compound meso-tetraphenylporphyrin. In situ oxidation neutral under ESI conditions produced singly charged cobalt(III) ions; free bases ionized by protonation. For porphyrinoids an intact porphyrin core, major pathways observed losses meso-substituent (for meso-phenyl groups) characteristic fragmentations one or more meso-substituents meso-thienyl group). Complex for modifications to core but chemically reasonable structures could be assigned most fragments, thus delineating general patterns pyrrole-modified porphyrins CID conditions.
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